It happened around 7:00 p.m. on Tuesday in the 200-block of Frederick Street.
Police say the suspects, one with a knife and the other with a gun, forced their way into a home and stabbed two men inside multiple times.
The victims were taken to Meritus Medical Center with non-life threatening injuries.
Four other people were also inside the home at the time of the attack including two children who escaped unharmed through a window.
Police believe the stabbing is drug related.
Anyone with information on the crime is asked to call police at (301) 790-3700.